1. Despite indicates an illogical occurrence.
We had a good time despite the bad weather.
2. In spite of has the same meaning and usage as despite.
We had a good time in spite of the bad weather.
Raama-Dut Atulit Bala-Dhaamaa |
Anjani-Putra Pavan-Sut Naamaa ||
You are the messenger of Shri Ram, O son of Anjani and Pavan you are the epitome of infinite strength and justly called ‘Pavan sut'